In the past few days, the story is aboutThe death of Anna Sebastian Perayil(26 years old) - Accountants working at Ernst & Young (EY) in Pune (India) are receiving the attention of public opinion, especially young people who have to work in a high -pressure environment.

The painful departure of the girl was written by Anita Augustine (Anna's mother) in the 3 -page letter to A4 pages to the president of EY Group.This letter exposed toxic culture at a large corporation, and pointed out the pressure and overloading time that indirectly pushed Anna to death.

It is unknown the cause of the girl's death but her mother shared, can see some important information: she had to go through a long time under the pressure of work,Regularly stay up late working, eat at night, do not have time to sleep, eat well.Before that, she often had a "breast spasm".Despite going to the doctor, the indicators were normal and consulted by the doctor, the girl continued to work and did not survive after a short time.From the above information, she is likely to have had silent myocardial anemia.

Silent myocardial anemia is a characteristic condition because blood flow to myocardial muscle is reduced without causing remarkable symptoms such as chest pain or shortness of breath like conventional myocardial infarction.Because there is no obvious symptom that makes it particularly dangerous, because people may not be aware of the hidden heart condition until there are dangerous complications.

Mechanism , silent myocardial ischemia is similar to myocardial infarction due to the imbalance between demand and oxygen supply.

Myocardial infarction is mainly caused by atherosclerotic plaques in the coronary artery, starting the process of forming blood clots, moving causing clogging later.Meanwhile, a number of reasons were given to explain why some patients with silent myocardial ischemia were due to: unable to reach the person's pain threshold;short ischemic attacks are not noticed;The higher β-endorphin concentration, more cytokine prevents the transmission of pain and awareness of changing pain or defects.Silent myocardial anemia follows the biological rhythm, with a higher incidence in the early morning.This phenomenon may be due to a number of hemodynamic or physiological factors that vary according to the biological rhythm, including heart rate and increased blood pressure, higher vasomotor energy, high levels of adrenergic and enhanced linksPlatelet practice.

The presence of silent ischemia is a strong death factor.About 70% to 80% of transient ischemia have no symptoms of angina (silent ischemia).Lack of pain in myocardial ischemia increases the incidence of disease and death because the patient does not seek medical treatment in time.

Risk factors leading to silent myocardial ischemia :

Risk factors of silent myocardial ischemia are closely in line with the risk factors of symptoms, including:

Family history of cardiovascular disease.

Smokers and use harmful stimulants.

I have metabolic disorders, high blood pressure.

Do not regularly exercise and exercise.Regularly staying up late, there is a disturbing biological rhythm.

Use daily food such as boxes, eating sugar, alcohol ...

In particular, mental stress can cause silent ischemia, especially in patients with potential coronary artery disease.Due to the chronic and acute stress agents that increase inflammatory reactions and autonomy imbalance, can lead to adverse effects on cardiovascular disease, endothelial dysfunction, abnormal blood vessel reactionand abnormal immune function.These factors eventually cause adverse cardiovascular events such as myocardial ischemia, myocardial infarction and arrhythmia.

Manifestation of Silent myocardial anemia:

Pain may be in the middle of the chest, lasting for a few minutes, spreading to the arm or spreading to the jaw.

The feeling of fatigue can last for a few days without the cause.Sometimes it feels full of epigastric, belching, swallowing easily confused with stomach disease.

Sometimes cold sweat is unknown, shortness of breath when operating.

Diagnosis of silent myocardial ischemia Meeting many challenges due to no remarkable symptoms, often have to be accidentally detected in the regular medical examination process or through diagnostic tests such as electrocardiograms (ECG), exertion or shooting testing.Coronary artery.Although there are no symptoms, silent myocardial ischemia increases the risk of serious complications such as myocardial infarction, heart failure and sudden heart.Screening individuals with risk factors for coronary artery disease is essential for early detection of silent myocardial ischemia.

To minimize potential risk factors and improve coronary blood flow through lifestyle changes (including aspirin, statin, β and CCB blockers) and in some cases, the playersCrossing techniques such as coronary artery or coronary artery bridge.

The prognosis depends on factors such as the level of potential, effective treatment and the accompanying pathological conditions.Early detection and appropriate management are important to improve results and reduce the risk of complications.Patient education plays an important role in raising awareness of silent myocardial ischemia, emphasizing the importance of periodic health checks, lifestyle changes and adherence to minimizing them.The risk of complications, especially in people with the above cardiovascular risk factors.

Through the above story, young people need to know the balance between work and life, as well as changing in the culture working at companies so that young people can promote their abilities, andThere is a good health, a dedicated work spirit.